Certification Board of Infection Control and Epidemiology (CBIC) Practice Exam 2025 - Free CBIC Practice Questions and Study Guide

The correct choice emphasizes the importance of the route of exposure in the context of rabies infection and the necessity for post-exposure prophylaxis (PEP). Close contacts of a rabies infection patient should receive PEP when there has been close mucous membrane exposure because this type of contact presents a significant risk for transmission of the rabies virus. Mucous membranes, such as those in the mouth, eyes, or nose, can allow the virus to enter the body easily, making it imperative to initiate PEP to prevent the onset of rabies, which is almost universally fatal once symptoms appear.

While bites from suspected rabid animals also warrant PEP due to the high risk of viral transmission through saliva, the emphasis here on mucous membrane exposure underscores a critical aspect of transmission routes that can occur even without a bite. Initiating PEP promptly in these situations is vital for effective prevention.

On the other hand, waiting until symptoms develop or only treating after a bite from a suspected rabid animal does not offer the protective measures required, as rabies is extremely dangerous, and once clinical symptoms manifest, the outcome is typically fatal. Using this understanding, it is clear that timely action following mucous membrane exposure is crucial in rabies management and prevention